Toss in additional mana discounts like Cloud Key and Ugin, the Ineffable, and a lot of the cheaper colorless creatures are going to be free to cast
If you have a way to give Earthquake Dragon haste, with say Concordant Crossroads or Lightning Greaves, for example, then your opponents will be staring down a 10/10 flyer with trample the turn it is played
If a player knows that their opponent has several key cards in their deck with the same converted mana cost, Chalice of the Void can be the death knell
Some commanders I could really see abusing this strategy besides Sigarda, Host of Herons are Thantis, the War Weaver , Tajic Blade of the Legion , Sapling of Colfenor and any of the Amonkhet Gods
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