Reviews (5) Description FAQ Description GHK-Cu is commonly referenced in collagen biology, skin matrix research, and hair follicle studies
Routes of Administration AHK-Cu's route in community use is topical only
It is studied for its potential in tissue remodeling and cellular response pathways without systemic effects
Predrag Sikirics group (School of Medicine, University of Zagreb, 1991 ) Most common experimental dose in animal studies: 10 g/kg intraperitoneally or per os, daily Standard targeted pathways: VEGFR2 angiogenesis, NO synthase , 5-HT2A serotonin receptor, dopamine D2 receptor Clinical program in Croatia halted at Phase 2 (Crohns disease) WADA Prohibited List: added in 2022 to category S0 (Non-Approved Substances) Reference sources (PubMed) Sikiric P
The IRR is upregulated in injured brain tissue following trauma, and its activation by ARA-290 reduced neuronal apoptosis, microglial-mediated neuroinflammation, and functional deficits in animal models