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The recommendation to combine GHK-Cu and retinol is mechanistically rational, but honest framing requires acknowledging that it is based on mechanistic reasoning and tolerability data rather than a direct clinical trial of the combination
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Furthermore, as a result of their pleiotropic effect on multiple organ systems, these agents are emerging as potential therapy for metabolic dysfunction-associated steatotic liver disease, neurodegenerative conditions, and behavioral health disorders [5, 6]
doi: 10.1113/jfisiol.2013.255364
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