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The more you shock your body, the more it goes into panic mode, and when youre losing 30% of your body weight in 12 weeks, thats a crisis metabolically. With HU6, Khan explained, were able to increase our patients metabolism in modest ways, but that over the treatment durations lead to fat-specific weight loss that is very meaningful. Trial participants taking HU6 have lost three to four pounds per monthconsistently, Dallas said
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However, the GLP-1R-expressing cell types that mediate these effects are not known, although recent studies showed atrial GLP-1R-mediated regulation of blood pressure in mice [11]
10.1073/pnas.96.6.3059 Proc
