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The most commonly reported quality-of-life concerns, ranked by frequency in a 2021 patient-reported outcomes survey of 890 US women taking spironolactone for acne (published in JAAD Open , N=890), were: Source

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Be Patient: Results typically take 1 to 3 months of daily use

Ask your healthcare provider about prescription or OTC remedies for heartburn

Albulushi A, Tanoh DB, Almustafa A et al (2024) Comparative effects of glucagon-like peptide-1 receptor agonists and sodium-glucose co-transporter-2 inhibitors on heart failure with preserved ejection fraction in diabetic patients: a meta-analysis