Geniposide, acting as a GLP-1R agonist, partially prevented STZ-induced learning and memory impairment via modulation of PI3K/GSK-3 signaling pathway and reduced STZ-induced hyperphosphorylation of tau protein (220)
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Growing attention has been paid to the relationship between GLP-1RAs and tumorigenesis, development, and prognosis in patients with T2DM
Why they matter: Large randomised cardiovascular and renal outcome trials (EMPA-REG OUTCOME, DAPA-HF, DAPA-CKD, EMPEROR-Reduced/Preserved, CREDENCE, EMPA-KIDNEY) consistently showed reductions in heart-failure hospitalisation, progression of chronic kidney disease, and cardiovascular death
According to the Centers for Disease Control and Prevention (CDC), there are several ways seniors can stay happy and healthy during this difficult time: Breakaway from news coverage