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Any laboratory work using the blend has to account for that asymmetry rather than treating the vial as a single 80mg unit

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Considering the putative role of oxidative stress as a pathogenetic factor for the development of colitis and because the reductive metabolism of TNBS has been shown to generate ROS, this model of colitis was chosen to evalute the temporal relationship between the levels of GSH in mucosa and the appearance and extent of injury in vivo during the acute phase of colitis in TNBS+ethanol-treated rats and to determine the effect of NAC administration on mucosal GSH levels and extent of injury

In fact, accumulated data show rotenone exposure to humans would most commonly involve ingestion 1

That generality cuts both ways: broad protective activity can indicate a fundamental cellular mechanism, or a non-specific effect difficult to translate into a targeted intervention