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The only isoform that is known to be inactive at basal intracellular calcium levels is the subfamily of enzymes suggesting that they function as calcium amplifiers that become activated downstream of other PLC family members
1999 Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells Oncogene 18 : 63806387 Sanchez A, Alvarez AM, Benito M, Fabregat I
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