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There is also no strong efficacy argument for rushing: in REDEFINE 2 only 61.9% of patients were on the full 2.4 mg at the end of the trial and the group still averaged 13.7%
Publications reported changes in retinal structure or function and proposed that the pineal gland and retina may share aspects of developmental or transcriptional regulation
People with cystinuria are naturally more likely to form cystine kidney stones
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