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rocuronium, vecuronium, atracurium, cisatracurium) It is not effective against depolarizing skeletal muscle relaxants (succinylcholine) It may be used adjunctively in the treatment of respiratory depression caused by overdosage of curare like neuromuscular blockers Contraindications: Known hypersensitivity to anticholinesterase agents Intestinal and urinary obstructions of mechanical type Side Effects: The myasthenic patient in crisis who is being tested with edrophonium should be observed for bradycardia or cardiac standstill and cholinergic reactions if an overdose is given

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Lancet 374 , 3947 (2009)

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These increases in decay and damage, and memory loss itself, can be partially reversed in old rats by feeding acetyl-L-carnitine

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That there exist interspecies differences in biosynthetic pathways mediated by gut microbiota metabolism between mice and humans is consistent with numerous other examples of how gut microbiomes of mammalian species can differ (44)

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