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Cholesterol also plays a significant role in solute partitioning into lipid membranes depending on lipid-cholesterol interactions (discussed earlier) with more pronounced effects for large solutes, membranes with less chain unsaturation, and membranes with smaller phospholipid headgroups [128]
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PKC isoforms localize due to compartment and signal-organizing scaffolds using receptors for activated C kinases (RACKs), A-kinase anchoring proteins (AKAPs), heat shock proteins (HSPs) as well as annexins (AnxA1, A2, A5, and A6) (Hoque et al., 2014)
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