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Ozempic, whose active ingredient is semaglutide, is designed to mimic the beneficial actions of natural GLP-1

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placebo in adults with overweight or obesity without diabetes (STEP 3), mean body weight decreased 16.0% with semaglutide compared with 5.7% with placebo, both as adjunct to intensive behavioral therapy (ETD 10.3%

The target hematocrit was 28% to 33% throughout the study, and a protocol for erythropoietin dosing was established

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