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Another study focusing on individuals taking a 2.4 mg dose of semaglutide found that those who experienced diarrhea only dealt with the symptoms for about three days
doi:10.1016/S2213-8587(19)30066-X Data on file
Ohishi J, Aoki M, Nabeshima K, Suzumiya J, Takeuchi T, Ogose A, et al
AGT is present in the proximal tubule and concurrent increases in AGT-mRNA/protein in renal tissue homogenates has been explained as indicating that transcriptional activation of the AGT gene would be responsible for renal ANG II increase
While some individuals may notice changes within the first few weeks of treatment, significant effects usually become apparent after three to four months
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