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GLUCAGON-LIKE peptide-1 (GLP-1) receptor agonists use in patients with Type 2 diabetes is modestly associated with an increased rate of erectile dysfunction, a 2026 target trial emulation has found
The viral off-label usage for weight loss prompted both companies to rebrand and repurpose their diabetes meds to obesity treatments under new labels with higher doses called Wegovy and Zepbound
doi:10.1007/978-1-4939-0620-8_39
PubMed, doi:10.1016/j.envpol.2017.10.079
However, it's important to point out that in the Surmount-4 study, patients were given 2.5 mg of Zepbound and kept upping the dosage up to their maximum tolerated levels of 10mg or 15mg once weekly
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