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Tirapazamine sensitizes hepatocellular carcinoma cells to topoisomerase I inhibitors via cooperative modulation of hypoxia-inducible factor-1alpha

For homologous desensitization, islets were pre-incubated overnight with 100 nM agonist

Age-related declines in GH pulse amplitude are well-documented, associated with reductions in somatotroph responsiveness, increased somatostatin tone, and decreased hypothalamic GHRH output

Anti-Doping Agency (USADA) 3

It also has significant antioxidant effects and has been shown to inhibit carcinogenic receptor expression, which has led to research into its potential anti-tumor effects in breast and colorectal cancer [5, 6]