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Any spotting after menopause deserves prompt evaluation, including pelvic ultrasound and possible biopsy
treatment with glucose-lowering medication other than metformin 3 months prior to screening (except short-term insulin treatment in connection with intercurrent illness)
Obesity is a chronic condition requiring long-term medication management
At lower doses the risk may be smaller, but strength training and adequate protein intake are non-negotiable complements to treatment
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