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Mechanistic studies show that hemin suppresses CBS expression to inhibit the TSS pathway and de novo cysteine biosynthesis

Critically, supersulfides, such as glutathione persulphide (GSSH), directly scavenge ferroptosis-implicated free radicals, notably LOO, via rapid hydrogen-atom transfer [224], while concurrently suppressing key ferroptotic drivers including inflammatory cytokines [225] and lipid peroxidation end-products (4-HNE) [226]

Glutathione is involved in regulating the genes and the production of cytokines that cause chronic inflammation

The 2004 study documented reduced loss of righting reflex, the rodent equivalent of losing consciousness from alcohol

PubMed, Zhao, Bao, et al