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Following both lumbar and ventricular CSF collections, 150 l of samples was transferred to a micro cryotube (Azenta Life Sciences, 67-0753-11 FluidX, Burlington, MA, USA), labeled with subject ID, spun at 4 C, flash frozen in liquid nitrogen, and stored at 80 C until analysis
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In contrast to prior studies 9,12,14,15 , which primarily relied on baseline or intention-to-treatstyle exposure definitions, AHM exposure in the present study was measured throughout the follow-up, and participants with high exposure ( 80% PDC) of the medication class were grouped under the class and compared, an approach not utilised in previous studies 9,12,13,15,31
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Hong S-Y, Gil H-W, Yang J-O, et al
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