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at China Pharmaceutical University and Nanjing First Hospital: oral Dihexa restored spatial learning and memory in the APP/PS1 transgenic mouse model of Alzheimers disease via the PI3K/AKT signaling pathway, reduced neuroinflammation, and preserved hippocampal synaptophysin expression (Sun et al., Brain Sciences 2021)
Although previous studies by Chen and Wu (153) suggest that PregS activates TRPV1, also known as the capsaicin receptor, other members of the TRPV and TRPM subfamily tested by Wagner and colleagues were not activated by PregS
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For the vast majority of peptides, yes, its the ideal diluent
