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The key shift we need The question is no longer: Can patients stop GLP-1s without regaining weight? It is: Which patients can taper, how slowly, with what lifestyle support, and with what monitoring? Until trials are designed to study deprescribing strategies, weight regain after abrupt withdrawal should not be framed as inevitability

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2-Ketoadipic Aciduria The formation of 2-ketoadipic acid is formed from the oxidation of through lysine, tryptophan, and hydroxylysine