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TS inhibition by 5FU regulates mitochondrial biogenesis through mTORPGC1 signalling 5FU has a multimodal mechanism of action: promoting DNA damage directly via its metabolite FdUTP or by inhibition of TS via FdUMP, depleting the pool of thymidine available for DNA synthesis, and causing RNA damage via FUTP (Fig
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doi: 10.3390/cells8090953 178 WangJYanSLuHWangSXuD
Lead solder was commonly used to connect copper water pipes in homes and buildings until Congress banned the use of lead solder in 1987
eNOS plays an important role in the regulation of colonic inflammation: A novel therapeutic target and a predictive marker for the prognosis of ulcerative colitis
