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IL-15 is a tetra-alpha helix bundle cytokine that operates through trans presentation at the IL-15 receptor [91]
Interestingly, this nanoformulation increased the specificity for SeChry delivery to ovarian cancer cells, as the nanoparticles were functionalised with folate and cancer cells express more folate receptor, and therefore significantly reduced the toxicity against non-malignant cells
To test the effect of V2Rpp and Fab30 on formation of disulfide trapped complexes, the reactions were performed as described above
Presented for research literature review only Larsen ES et al
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