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Metformin 2500/3000mg a day + Glipizide 20mg/glibenclemide15-20mg/day Gliciazide 320mg/ Glimepride 6-8mg/day + Rosiglitazone 8mg/ Pioglitazone 45mg/day When should Insulin be used in Type 2 diabetes mellitus
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Preliminary clinical evidence supports this hypothesisstudies in obese individuals treated with tirzepatide have shown a downward trend in the apneahypopnea index (AHI), suggesting that tirzepatide may have a beneficial effect on sleep-disordered breathing (28)
Small molecule
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Metabolic Support: Studies indicate it could improve lipid profiles (such as cholesterol and triglyceride levels) while maintaining stable blood glucose and insulin levels
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