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It has also been associated with psychogeriatric dis-ease, depression, high neurotoxin activity, and a decrease in intellectual function such as episodic and visuospatial memory, attention, and abstract reasoning (4, 20).Reynolds and colleagues found that 17 out of 24 hospitalized patients (71%) presenting severe folic acid deficiency were diagnosed with depression (46)
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191 In one randomized controlled trial that included 175 men with infertility, taking a supplement providing 1 gram L-carnitine and 0.5 grams acetyl-L-carnitine, as well as 725 mg fumarate, 1 gram fructose, 50 mg citric acid, 10 mg zinc, 20 mg CoQ10, 50 mcg selenium, 90 mg vitamin C, 200 mcg folic acid, and 1.5 mcg B12, twice daily improved sperm motility, semen volume, and DNA fragmentation compared with placebo after six months
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