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The sleep improvements, energy gains, and body composition changes gradually reverse over 2 to 6 months, depending on how long you were on therapy and how much of the benefit was maintained by lifestyle factors (exercise, sleep, diet)

doi: 10.1038/nature13270 79 MadirajuA

[29] Benzedrine sulfate was introduced 3 years later and was used to treat a wide variety of medical conditions, including narcolepsy, obesity, low blood pressure, low libido, and chronic pain, among others

It serves an endocrine function, providing IGF1R activation to peripheral tissues distant from the production site

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